Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension Running title: Lee et al.; Exosomes as paracrine vectors of MSC action
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چکیده
5 Pr Pr Pres es esen en nt t t Ad Addr dr d es es ss: s: s: U U Uni ni ive ve vers rs rsi it ity y y of of of C C Abstract: Background—Hypoxia induces an inflammatory response in the lung manifested by alternative
منابع مشابه
Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension.
BACKGROUND Hypoxia induces an inflammatory response in the lung manifested by alternative activation of macrophages with elevation of proinflammatory mediators that are critical for the later development of hypoxic pulmonary hypertension. Mesenchymal stromal cell transplantation inhibits lung inflammation, vascular remodeling, and right heart failure and reverses hypoxic pulmonary hypertension ...
متن کاملVascular Medicine Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension
Background—Hypoxia induces an inflammatory response in the lung manifested by alternative activation of macrophages with elevation of proinflammatory mediators that are critical for the later development of hypoxic pulmonary hypertension. Mesenchymal stromal cell transplantation inhibits lung inflammation, vascular remodeling, and right heart failure and reverses hypoxic pulmonary hypertension ...
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تاریخ انتشار 2012